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KMID : 0860920100120010048
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Journal of the Korean Association EMG-Electrodiagnostic Medicine
2010 Volume.12 No. 1 p.48 ~ p.50
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Multiple Cranial Neuropathies and Pupillary Areflexia Associated with Anti-GQ1b Antibody
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Oh Joo-Young
Choi Soo-Young
Lee Ji-Hee
Moon Jeong-Soo
Lee Ae-Young
Sohn Eun-Hee
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Abstract
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The causes of multiple cranial neuropathies are variable, including infection, inflammation or neoplastic lesion. They also can be a presenting features of the atypical variant of the Guillain-Barre syndrome (GBS). In spite of careful clinical investigation, etiology often remains unknown in many cases. We describe a patient who presented with ophthalmoplegia with pupillary areflexia, bulbar dysfunction, and bilateral facial palsy after upper respiratory tract infection and had significant elevation of anti-GQ1b antibody titer. We suggest that pupillary areflexia should be recognized as another feature that may be present in conditions of the anti-GQ1b antibody syndrome.
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KEYWORD
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Multiple cranial neuropathies, Pupil, Anti GQ1b antibody
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